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Srinath Palakurthi

Srinath Palakurthi
Srinath Palakurthi, PhD

Professor of Pharmaceutical Sciences

Contact

Texas A&M Irma Lerma Rangel School of Pharmacy
1010 W. Ave. B
Kingsville, TX 78363
palakurthi@tamu.edu
Phone: 361.221.0748
Fax: 361.221.0793
Generics Development Research Laboratory Brochure

Education and Training

  • Indian Institute of Chemical Technology, India, PhD in Pharmaceutics, 2000
  • Dr. H.S. Gour University, India, MPharm, Pharmaceutics, 1993
  • Kakatiya University, India, Bachelor of Science Pharmaceutical Sciences, 1990

Research Interests

  • Novel polymers for gene therapy
  • Polymer-based nanoparticles for targeted delivery of chemotherapeutics for the treatment of ovarian cancer
  • Mucosal delivery of chemotherapeutics and antigens
  • Cellular trafficking of nanoconstructs

Teaching Interests

  • Physicochemical and biopharmaceutical principles
  • Nanoparticles

Awards, Recognition and Service

  • Speaker at the 2nd World Conference on Magic Bullets (Ehrlich II) in Nurnberg, Germany
  • Speaker at the 8th International Conference of Anticancer Research in Kos, Greece
  • Reviewer for the Department of Defense (DOD)-Prostate Cancer Research Program (DOD-PCRP FY08)
  • Reviewer for the DOD-Peer Reviewed Medical Research Program (DOD-PRMRP FY08)

Representative Publications

  • Palakurthi, S., Wilson, J., McQuarrie, S.A., et al. (2008) “Target specificity of 188Re-labeled B27.1 monoclonal antibodies to ovarian cancer cells.” In vivo. 22(3):321-326.
  • Kumar, A., Yellepeddi, V., Guan, X., Davies, G., Palakurthi, S. (2008) “Enhanced gene transfection efficiency of ornithine-conjugated PAMAM dendrimers.” Journal of Pharmaceutical Science.
  • Pisal, D., Yellepeddi, V., Kumar, A., Palakurthi, S. (2008) “Transport of surface engineered polyamidoamine (PAMAM) dendrimers across IPEC-J2 cell monolayers.” Drug Delivery (in press).
  • Pisal, D., Yellepeddi, V., Kumar, A., Guan, X., Kaushik, R., Hildreth, M., Palakurthi, S. (2008) “Permeability of surface modified polyamidoamine (PAMAM) dendrimers across Caco-2 cell monolayers.”International Journal of Pharmaceutics. 350(1-2), 113-121.
  • Palakurthi, S.,  McQuarrie, S.A. and Suresh M.R. (2007) “Radiopharmaceutical Screening of 14C-polyamines in the AT3B-1 Rat prostate Tumor Model: A Search for a New PET Prostate Imaging Agent.” In vivo. 21, 823-828.