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Jayshree Mishra

Jayshree Mishra
Jayshree Mishra, PhD

Research Assistant Professor of Pharmaceutical Sciences

Contact

Texas A&M Irma Lerma Rangel School of Pharmacy
1010 W. Ave. B
Kingsville , TX 78363
jayshree.mishra@tamu.edu
Phone: 361.221.0963
Fax: 361.221.0798

Education and Training

  • Irma Lerma Rangel College of Pharmacy, Research Scientist, 2010-2014
  • ILR College of Pharmacy, Associate Research Scientist, 2008-2010
  • University of Tennessee, College Of Pharmacy, Post-doctoral Research Associate, 2006-2008
  • University of Tennessee, College Of Medicine, Post-doctoral Trainee, 2005-2006
  • Indian Institute of Technology, India, PhD, Microbial Biotechnology, 2005
  • Indian Institute of Technology, India, Masters in Technology, Applied Botany, 2000

Research Interests

  • Role of drug transporter proteins in colonic mucosal innate immunity.
  • Post-translational modification of drug transporter proteins and its role in Multidrug resistance.

Teaching Interests

  • Biochemistry
  • Microbiology

Awards, Recognition and Service

  • National Institutes of Health-Small Business Innovation Research (SBIR/STTR) award (Role: Co-Principal Investigator on University sub-contract)
  • Travel Award; Gordon Research Conference
  • Travel Award; Academic Skill Workshop organized by AGA Institute and AASLD Institute
  • Second Best Poster presenter award 1st Annual Research Colloquium-2010
  • DAAD Fellowship; Government of Federal Republic of Germany Type: Graduate scholarship to do advance research on hydrogen Biotechnology at Ruhr University, Bochum, Germany (2003-2004)
  • Jawaharlal Nehru Memorial Fund Award; India, Delhi Type: Ph.D. scholarship to continue research in India (2002-2003)
  • GI Investigator Development Research Award from ACCP Research Institute
  • Laboratory Mentor Award” for Upward Bound Math & Science program from Texas A&M University-Kingsville
  • “Certificate of Recognition for chairing the session” in Pharmacovigillence-2013.”
  • Awarding agency: OMICS Publishing Group.
  • Organizing committee member of International Conferences *Pharmacovigillence-2013, San Antonio, Texas; *Pharmacovigillence-2014, Hyderabad, India; *World Nutraceutical Conference and Expo-2015, Philadelphia, Penn.
  • Graduate Aptitude Test in Engineering Scholarship Awarding agency: Department of Biotechnology, Government of India Type: To pursue Master of Technology in Indian Institute Of Technology, India (1998-2001)

Patents

  • Kumar N, and Mishra J. A Novel High Throughput Assay for finding new Jak3 Interacting Compounds, Biomolecules, and Inhibitors. U.S. Provisional patent number 61/960652. (Currently under negotiation for licensing)

Representative Publications

  • Mishra, J., and Kumar, N. (2014) Adapter protein shc regulates Janus kinase 3 phosphorylation. J Biol Chem(Accelerated Publication) 289(23):15951-6 Corresponding author.
  • Mishra, J., Verma, R. K., Alpini, G., Meng, F., and Kumar, N. (2013) Role of Janus kinase 3 in mucosal differentiation and predisposition to colitis. J Biol Chem 288, 31795-31806.
  • Mishra, J., Drummond, J., Quazi, S. H., Karanki, S. S., Shaw, J. J., Chen, B., and Kumar, N. (2013) Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis. Critical reviews in oncology/hematology 86, 232-250.
  • Mishra, J., Waters, C. M., and Kumar, N. (2012) Molecular mechanism of interleukin-2-induced mucosal homeostasis. Am J Physiol Cell Physiol 302, C735-747.
  • Mishra, J., Karanki, S. S., and Kumar, N. (2012) Identification of molecular switch regulating interactions of Janus kinase 3 with cytoskeletal proteins. J Biol Chem (Accelerated publication )287, 41386-41391.
  • Mishra J, Zhang Q and Neudeck B. Activation of TLR-4 receptor increases cell surface P-glycoprotein expression with decreased activity(2008)Drug Metabolism and Disposition Oct;36(10):2145-9,
  • Mishra J, Khurana S, Kumar N, Ghosh AK, Das D.  Molecular cloning, characterization, and over expression of a novel [Fe]-hydrogenase isolated from a high rate of hydrogen producing Enterobacter cloacae IIT-BT 08(2004). Biochem Biophys Res Commun. 324: 679-685.
  • Kumar N, Mishra J, Narang VS, Waters CM.  Janus Kinase 3 (Jak3) regulates interleukin induced mucosal wound repair through tyrosine phosphorylation of villin.(2007)J Biol Chem (Accelerated publication) .,282(42), 30341-30345/