Dr. Mohammad Nutan's Lab

Research Goals

The Nutan lab focuses on three areas:

• Preformulation and stability studies
• Formulation studies
• Analytical studies 

Preformulation and stability studies
Preformulation studies are performed to physicochemically characterize new active and inactive ingredients. Stability studies are done to determine the shelf life of products. Our lab performs both studies involving drug and drug products. We also have experience in synthesizing and conducting physical, chemical, and mechanical characterization of polymers and preparing and performing physical characterization of polymeric dispersions for coating solid dosage forms.

Formulation studies
This is our primary area of research. We have expertise in developing any type of drug products including tablets, capsules, beads, microparticles, and injectable implant systems with optimum properties utilizing Quality by Design approach. We also developed various complex drug delivery systems for (i) improving bioavailability of drugs, e.g., solid-lipid nanoparticles of curcumin, semisolid preparations of mefenamic acid coprecipitates for topical delivery, self-nanoemulsified systems of coenzyme Q₁₀ and ergocalciferol, bilayered tablet of salmon calcitonin and (ii) controlled release of drugs, e.g., multiparticulate bead system coated with starch acetate, osmotic tablets for intestinal drug delivery of salmon calcitonin, in situ injectable and microparticle formulations containing biocompatible polymers, and mucoadhesive microparticles of indomethacin.

Analytical studies
Our lab also has expertise in analyzing formulation and biological samples containing drugs. Our previous studies included quantitative analyses of drug and impurities in tablets purchased through internet.