Zakaria Abd Elmageed
Zakaria Abd Elmageed, PhD
Assistant Professor in Pharmaceutical Sciences
Curriculum Vitae
Contact
Texas A&M Irma Lerma Rangel College of Pharmacy
1010 W. Ave. B
Kingsville,
TX
78363
elmageed@tamu.edu
Phone: 361.221.0733
Fax: 361.221.0793
Education and Training
- Tulane University School of Medicine, Postdoctoral training , Urology Department, 2009 - 2011
- Johns Hopkins School of Medicine, Postdoctoral training, Division of Endocrinology, 2008 - 2009
- LSU Health Sciences Center, School of Medicine, Postdoctoral training, Pathology Department, 2006 - 2008
- Helwan University, PhD in Biology and Biochemistry, 2004
- Helwan University, Master of Science in Physiology, 1999
- Cairo University, Bachelor of Science with Honor, Biology, 1995
Research Interests
- Prostate cancer progression using in vitro, in vivo and human samples approaches
- Cancer Biomarkers
- Drug Resistance
- microRNAs and Exosomes
- Cell signaling and therapeutic targets
Teaching Interests
- Oncology
- Pharmacology
- Biochemistry
- Molecular Biology
Awards, Recognition and Service
- Scientific Judge in the AACR Career Development and Mentoring Committee during the Eleventh Annual AACR Undergraduate Student Caucus and Poster Competition. April 16, 2016, New Orleans, LA. 2016
- Oral presentation in The American Association of Endocrine Surgeons. Baltimore, MD. April 09-12, 2016. Title: Synergistic effects of BRAF and proteasome inhibitors for treating aggressive thyroid cancer. Tsumagari K, Abd Elmageed Z. et al. 2016
- R21 NCI/NIH Award. Title: The role of exRNA in health disparity of prostate cancer (PI: Abd-Elmageed ZY). 2015
- Louisiana Clinical & Translational Science Center (LaCaTS) for translational research (PI: Abd-Elmageed ZY). Title: Discovering the role of putative microRNAs in prostate tumorigenesis. 2013
- National Center for Advancing Translational Sciences (NCATS) Award ($4.2 million grant). Abdel-Mageed AB (PI), Mondal D (Co-I) and Abd Elmageed ZY (Co-I). 2013
- Oral presentation-Academic Surgical Congress, February 4-7th. Title: Simultaneous suppression of the MAP kinase and PI3K/Akt pathways in aggressive thyroid cancer. Li X, Abd Elmageed ZY, Kandil E. 2013
- Oral presentation-Academic Surgical Congress, February 4-7th. Title: CD146-Latexin crosstalk and their potential role in thyroid tumorigenesis. Abd Elmageed ZY et al. 2013
- One of the top 10 abstracts at the 19th Annual Fall Scientific Meeting of the Sexual Medicine Society of North America. The award resulted in an oral presentation. See Invited Talks. Oral presentation and Title: Early combined treatment with Avanafil and adipose tissue-derived stem cells promotes recovery of erectile function in a rat model of postprostatectomy induced erectile dysfunction. Gokce A, Abd Elmageed ZY, et al. 2013
- First place Award-Poster presentation-American Association of Head and Neck Surgery, Chicago. 2011
- Fellowship Award for Postdoctoral training- Ministry of Higher Education, Cairo. 2006
- Teaching Faculty Award-Faculty of Science-Helwan University. 2005
Patents
- In vitro and in vivo Tetracycline inducible fluorescently-tagged protein expression system. Inventor: A Ouhtit (PI), Abd Elmageed, ZY (Co-PI), M Zerfauoi (Co-PI). Invention serial number: 60/956,437. LSU Health Sciences Center, LA, 2010.
Representative Publications
- Abd Elmageed ZY, Sholl AB, Tsumagari K, Al-Qurayshi Z, Basolo F, Moroz K, Boulares H, Friedlander P, Miccoli P, Kandil E. Immunohistochemistry as an Accurate Tool for Evaluating BRAF-V600E Mutation in 130 Samples of Papillary Thyroid Cancer. Surgery, 2016 Dec 2. pii: S0039-6060(16)30722-X.
- Abdel Wahab AH, El-Halawany MS, Emam AA, Elfiky A, Abd Elmageed ZY. Identification of circulating protein biomarkers in patients with hepatocellular carcinoma concomitantly infected with chronic hepatitis C virus. Biomarkers. 2016 Nov 10:1-8. [Epub ahead of print]
- Gur S, Rezk BM, Abd Elmageed ZY, Kadowitz PJ, Sikka SC, Hellstrom WJ. Characterization of pomegranate juice effects on human corpus cavernosum. Andrologia. 2016 Oct 26. doi: 10.1111/and.12712.
- El-Bahrawy AH, Tarhuni A, Kim H, Subramaniam V, Benslimane I, Elmageed ZY, Okpechi SC, Ghonim MA, Hemeida RA, Abo-Yousef AM, El-Sherbiny GA, Abdel-Raheem IT, Kim J, Naura AS, Boulares AH. ApoE deficiency promotes colon inflammation and enhances the inflammatory potential of oxidized-LDL and TNF-α in primary colon epithelial cells. Biosci Rep. 2016 Nov 17;36(6). pii: e00408. Print 2016 Dec.
- El Jamal SM, Taylor EB, Abd Elmageed ZY, Alamodi AA, Selimovic D, Alkhateeb A, Hannig M, Hassan SY, Santourlidis S, Friedlander PL, Haikel Y, Vijaykumar S, Kandil E, Hassan M. Interferon gamma-induced apoptosis of head and neck squamous cell carcinoma is connected to indoleamine-2,3-dioxygenase via mitochondrial and ER stress-associated pathways. Cell Div. 2016 Aug 2;11:11. doi: 10.1186/s13008-016-0023-4.
- Anwar M, Murad F, Dawson E, Abd Elmageed ZY, Tsumagari K, Kandil E. Immunohistochemistry as a reliable method for detection of BRAF-V600E mutation in melanoma: a systematic review and meta-analysis of current published literature. J Surg Res. 2016. 15;203(2):407-15
- Moore RF, Sholl AB, Kidd L, Al-Qurayshi Z, Tsumagari K, Emejulu OM, Kholmatov R, Friedlander P, Abd Elmageed ZY, Kandil E. Metadherin Expression is Associated with Extrathyroidal Extension in Papillary Thyroid Cancer Patients. Ann Surg Oncol. 2016 May 4. [Epub ahead of print]
- Katz EG, Moustafa AA, Heidenberg D, Haney N, Peak T, Lasker GF, Knoedler M, Rittenberg D, Rezk BM, Abd Elmageed ZY, Yafi FA, Sikka S, Abdel-Mageed AB, Hellstrom WJ. Pioglitazone Enhances Survival and Regeneration of Pelvic Ganglion Neurons After Cavernosal Nerve Injury. Urology. 2016 Jan 6. pii: S0090-4295(15)01165-6.
- Elzamly S, Elbalshy A, Abuhashim M, Saad E, Agina HA, Abd Elmageed ZY*. Integration of VEGF and α-SMA expression improves the prediction accuracy of fibrosis in chronic Hepatitis C liver biopsy. Appl Immunohistochem & Mol Morphol. 2016 Mar 17. [Epub ahead of print]
- Yang Y, Jia D, Kim H, Abd Elmageed ZY, Datta A, Davis R, Srivastav S, Moroz K, Crawford B, Moparty K, Thomas R, Hudson RS, Ambs S, Abdel-Mageed AB. Dysregulation of microRNA-212 Promotes Castration Resistance via hnRNPH1-Mediated Regulation of AR and AR-V7: Implications for Racial Disparity of Prostate Cancer. Clin Cancer Res. 2016 Apr 1;22(7):1744-56.