Mahua Choudhury

Biography

Ongoing projects:

Lab is involved in several research projects related to the area of metabolism as it interacts with epigenetics. The research is currently emphasized on the

(1) Biology of Disease – Identifying and understanding molecular errors leading to metabolic syndrome and pregnancy complications at basic, translational, and clinical level

(2) Molecular Diagnostics – Developing non-invasive epigenetic markers and point of care diagnostic for diabetes, obesity, and preeclampsia as early as first trimester

(3) Nutritional or RNA therapeutic approaches that modulate or correct molecular errors in disease.

Project 1: Effect of Western Diet on Epigenetic and Non-coding RNA Regulation in Metabolic Syndrome and Transgenerational Inheritance (NAFLD/Atherosclerosis/Adipogenesis)

Project 2: Effect of Endocrine Disruptors on Epigenetics and Long non coding RNA in Metabolic syndrome (NAFLD/Atherosclerosis/Adipogenesis)

Project 3: Nutraceuticals in Disease Prevention (microRNA, HAT, and HDACs perspective- NAFLD/Atherosclerosis/Adipogenesis)

Project 4: Stem cell regulation, therapy, and microbiome in metabolic diseases

Project 5: Early first trimester epigenetic and microRNA Biomarkers in preeclamptic patients and reversal

Project 6: A Sensitive miRNA Tool for prediction of preeclampsia

Project 7: Aging and metabolic disorders: A vicious cycle

Project 7: Antioxidants infused hydrogel

Project 8: Epigenetic and miRNA biomarkers in noninvasive human samples

Project 9: Social disparity in birth defect and epigenetic regulation

Project 10: Epigenetic regulation in iPSC and HSC