Mahua Choudhury

Associate Professor, Department of Pharmaceutical Sciences
Morris L Lichtenstein Jr Medical Research Scientist
Co-Director of Center for Microencapsulation and Drug Delivery
Graduate Faculty Nutrition Department
Graduate Faculty, Interdisciplinary Graduate Program in Genetics
TAMHSC Postdocs Advisor
Contact
Mail Stop 1114
159 Reynolds Medical Building
College Station
, TX
77843-1114
drmc@tamu.edu
Phone: 979.436.0773
Fax: 313.436.0087
Choudhury's Lab
Biography
Ongoing projects:
Lab is involved in several research projects related to the area of metabolism as it interacts with epigenetics. The research is currently emphasized on the
(1) Biology of Disease – Identifying and understanding molecular errors leading to metabolic syndrome and pregnancy complications at basic, translational, and clinical level
(2) Molecular Diagnostics – Developing non-invasive epigenetic markers and point of care diagnostic for diabetes, obesity, and preeclampsia as early as first trimester
(3) Nutritional or RNA therapeutic approaches that modulate or correct molecular errors in disease.
Project 1: Effect of Western Diet on Epigenetic and Non-coding RNA Regulation in Metabolic Syndrome and Transgenerational Inheritance (NAFLD/Atherosclerosis/Adipogenesis)
Project 2: Effect of Endocrine Disruptors on Epigenetics and Long non coding RNA in Metabolic syndrome (NAFLD/Atherosclerosis/Adipogenesis)
Project 3: Nutraceuticals in Disease Prevention (microRNA, HAT, and HDACs perspective- NAFLD/Atherosclerosis/Adipogenesis)
Project 4: Stem cell regulation, therapy, and microbiome in metabolic diseases
Project 5: Early first trimester epigenetic and microRNA Biomarkers in preeclamptic patients and reversal
Project 6: A Sensitive miRNA Tool for prediction of preeclampsia
Project 7: Aging and metabolic disorders: A vicious cycle
Project 7: Antioxidants infused hydrogel
Project 8: Epigenetic and miRNA biomarkers in noninvasive human samples
Project 9: Social disparity in birth defect and epigenetic regulation
Project 10: Epigenetic regulation in iPSC and HSC

Education and Training
- University of Colorado, Aurora, Colorado, Research Instructor of Pediatrics, Neonatology, September 2011-September 2012
- University of Colorado, Aurora, Colorado, Postdoctoral Fellow of Pediatrics, Neonatology, August 2008-August 2011
- University of Missouri-Columbia, Columbia, Missouri, PhD, Medical Pharmacology, 2008
- University of Calcutta, India, Master of Science in Molecular Biology, Biophysics & Genetics, 2001
- University of Calcutta, India, Bachelor of Science in Zoology, Botany, Chemistry, 1999
Research Interests
- Prediction of disease risk
- Genes and the environment
- Pathology
Teaching Interests
- Principles of drug action
- Endocrinology
Representative Publications
- Choudhury M* & Jacob E. Friedman. Epigenetics and micro-RNAs in Preeclampsia. Clinical and Experimental Hypertension 2012 *Corresponding Author. PMID: 22468840
- Choudhury M & Jacob E. Friedman. Childhood obesity: methylate now, pay later? Nature Reviews Endocrinology 2011; 7(8):439-40 PMID: 21691305
- Choudhury M, Karen R. Jonscher, and Jacob E. Friedman. Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat. Aging (Albany NY) 2011; 3(2):175-8. PMID: 21386135
- Choudhury M, Pandey RS, Clemens DL, Davis JW, Lim RW, Shukla SD. Knock down of GCN5 histone acetyltransferase by siRNA decreases ethanol-induced histone acetylation and affects differential expression of genes in human hepatoma cells. Alcohol 2011 PMID: 21367571